Effect of Diabetes Type on USA SPK Outcome for 1998 - 2003 Cases

Since 1994, transplant centers reported recipients as diabetes type 1 or type 2. Of 1999-2003 primary DD recipients, 6% SPK, 4% PAK and 3% PTA were classified by the reporting centers as type 2.  For SPK, mean recipient age range was 40+8 years for type 1 (n=3479) and 44+8 years for type 2 (n=231) (p=0.003).  Neither patient survival rates nor pancreas graft survival rates had statistically significant differences in SPK type 1 and type 2 cases.  For type 1, patient survival at 1 year was 95% and pancreas graft survival was 84.8%; for type 2, rates were 93% and 85.2% respectively. By HLA phenotype, DR 3 or 4 or both antigens was expressed in 51% of type 1 vs. 47% of type 2.

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