Demographic US Cases

Table 9 shows the basic demographics for deceased donor (DD) primary US pancreas transplants reported to UNOS from January 1, 2000 to June 6, 2004 (71% SPK, 21% Pak, 8% PTA). SPK is the largest category, with a significantly higher percentage of minorities, significantly longer waiting time and the highest rate of Human Leukocyte Antigen (HLA) A, B and DR mismatches. Most SPK pancreas transplants are now enteric drained (ED) for duct management. PAK is the next largest category where all recipients already underwent a kidney transplant. PAK recipients are the oldest, have the longest duration of diabetes and a high HLA mismatch rate. PTA is the smallest category. PTA recipients are generally younger and thus have a shorter duration of diabetes. Waiting list time is shorter for the PTA category, but preservation time is longer compared to SPK. Significantly more females than males receive a PTA. The proportion of ED grafts is the lowest in PTA compared to SPK and PAK.

Table 9. Demographics for US DD primary pancreas transplants 1/1/2000 – 6/2004

	SPK	PAK	PTA	p - value
Number of Transplants	3,947 (71%)	1,149 (21%)	453 (8%)	-
Recipient age [years]	40.6 ± 8.3	41.4 ± 7.7	40.4 ± 9.4	0.002
Male recipients	59.6%	57.4%	41.9%	0.0001
Percent minorities	20%	13%	5%	0.0001
Diabetes durination [years]	26.4 ± 7.8	28 ± 8.0	25.3±10.4	0.0001
Percent ED	81%	67%	56%	0.0001
Percent of portal drained ED	20%	23%	35%	0.0001
Preservation time [hours]	13.3 ± 5.9	15.3 ± 5.5	16.2 ± 5.8	0.0001
Donor age [years]	26.7 ± 11.0	26.9 ± 11.0	27.2 ± 11.4	0.17
No. of HLA A, B, Donor mismatches	4.6 ± 1.3	4.2 ± 1.3	3.9 ± 1.5	0.0001
Waiting list time median months 25% - 75%	9.5 4-17	5.1 2-11	2.9 1-8.3	0.0001

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