By duct management technique, bladder drained (BD) versus enteric drained (ED) pancreas graft survival rates (GSRs) at one-year for 2000-2004 US DD primary SPK cases were BD 87% and ED 85% (Figure 8); kidney GSRs were BD 91% and ED 93% (Figure 9). Patient survival rates were 94% and 96% respectively. GSR differences were not significant, but the slight patient survival rate difference was confirmed significant in multivariate analysis.
Figure 8
Figure 9
For 2000-2004 US DD primary PAK cases, pancreas GSRs at 1-year (Figure 10) for ED were lower than for BD, but not significantly. PTA 1-year GSRs (Figure 11) with BD were also higher than ED, but not significantly. Patient survival differences at one year for PAK and PTA were not significant: PAK 96% BD, 95% ED; PTA 97% BD, 98% ED.
Figure 10
Figure 11
Duct Management information was reported for 60% of non-US SPK cases. In a comparison to US SPK cases for the same period, BD showed no differences while ED showed slightly higher GSRs for non-US cases (Table 2). The difference may be explained by the lack of follow-up and the incomplete information on non-US cases should also be noted.
Table 2. Comparison of Non-US vs. US SPK patient survival and graft function by duct management technique (DD primary pancreas transplants 1/1/2000 – 6/2004)
| |
|
BD
|
ED
|
p
|
| |
|
N % |
N % |
|
| Pt Survival |
Non USA
USA |
143 91%
707 94% |
764 96%
3047 96% |
NS
P = 0.05 |
| |
p |
NS |
NS |
|
| Px Survival |
Non USA
USA |
143 79%
707 87% |
764 89%
3047 85% |
NS
NS |
| |
p |
NS |
p = 0.05 |
|
| Kd Survival |
Non USA
USA |
143 83%
707 91% |
764 94%
3047 93% |
p = 0.04
NS |
| |
p |
NS |
NS |
|
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